System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol Cell. 2016 Mar 2.
DNA-controlled dynamic colloidal nanoparticle systems for mediating cellular interaction. Science. 2016 Feb 19.
Pooled screening for antiproliferative inhibitors of protein-protein interactions. Nat Chem Biol. 2016 Feb 22.
Tailoring nanoparticle designs to target cancer based on tumor pathophysiology. Proc Natl Acad Sci U S A. 2016 Feb 16.
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. 2016 Jan 07.
Driving Innovation in Medicine
Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
Your gift to the Donnelly Centre allows researchers to explore new and innovative ideas that will transform our understanding of biology. It supports discovery that will unearth the cause of human disease, advance diagnosis and disease detection, create personalized therapies, and reverse injury through regenerative medicine.